ADME

Metabolism - Excretion - Urinary System

Ureter and Bladder

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Excretory passages

Minor & Major calyces Renal pelvis Ureter

Slide 78 Urinary bladder
Slide 79 Urethra

Excretory passages

3 layers
  • Mucosa
    • Transitional epithelium
    • Subendothelial CT
  • Muscle layer
  • Adventitia
Ureter Slide 78

Ureter

  • Transitional epithelium
    • Thicker than calyces
    • More cell layers
  • Muscle
    • Upper 2/3 Inner longitudinal Outer circular
    • Lower 1/3 Inner longitudinal Middle circular Outer longitudinal

Urinary bladder

Slide 79

Urinary bladder

  • Transitional epithelium
    • Scalloped contour
    • Due to dome-shaped surface cells
  • Thin basal lamina on fibro-elastic CT
  • Muscle
    • Inner longitudinal
    • Middle circular
    • Outer longitudinal

Urethra Male

  • 3 Parts
  • Prostatic
    • Transitional epithelium
  • Membranous &
  • Cavernous
    • Pseudostratified to columnar
  • Thin basement membrane on
    • Subepithelial CT with
    • Mucous secreting glands (Littré)
  • Muscle
    • Inner longitudinal Outer circular
    • Distal end stratified squamous > Skin

Urethra Female

  • Primarily stratified squamous epithelium
  • Patches pseudostratified columnar
  • Thin basement membrane on
    • Subepithelial CT with
    • Mucous secreting glands (Littré)
  • Muscle
    • Inner longitudinal Outer circular
    • Distal end stratified squamous > Skin

The End

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