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Spinal cord

   

Overview

Franz Nissl

Clinical anatomy

Sagittal section of a vertebral column

Workbook tasks

Slide 26: Spinal cord - multipolar neurons

H/E

This is a cross section through the spinal cord and spinal ganglion. The spinal cord serves as an example of multipolar neuron cell bodies. The spinal ganglion is used as an example to demonstrate pseudo-unipolar neuron cell bodies.

Identify:

Macroscopic

  • The orientation of the spinal cord, identifying the H-shaped grey matter, the white matter and the spinal ganglion.

  • Locate the spinal ganglion next to the spinal cord. The pseudo-unipolar neurons are found in the spinal ganglion.

Microscopic

  • Longitudinal grooves

  • White matter

  • Grey matter

  • Central canal

  • The multipolar neuron cell bodies found in the grey matter.

    1. Cell body.
    2. Nucleus
    3. Nissl-substance
    4. Axon hillock
  • Nuclei of the neuroglia

  • The pseudo-unipolar neuron cell bodies found in the spinal ganglion.

    1. Cell bodies
    2. Nuclei
    3. Nissl-substance

 

Draw and annotate:

A cross sectional line diagram of the spinal cord.

A detailed diagram of a number of neurons, showing myelinated axons, ependyma and neurophils.

A multipolar neuron cell body. Indicate the components of the neuron in detail.

A pseudo-unipolar neuron.

 

Reflection:
  1. What is found in the longitudinal groove?
  2. What does the white matter consist of?
  3. What does the grey matter consist of?
  4. What does the central canal carry?
  5. What characteristic of the cell bodies is used in the identification of multipolar neurons?
  6. What is characteristic of the nuclei of the neurons?
  7. How does the Nissl-substance appear and what is it in reality?
  8. What is characteristic of the axon hillock?
  9. What is characteristic of the shape of a pseudo-unipolar neuron in comparison to that of multipolar neurons?
  10. How do the granules of the Nissl-substance of pseudo-unipolar neurons differ from those of the multipolar neurons?
 

Slides

Microscope

The spinal cord
Detail of the grey matter of the spinal cord
Detail of the grey matter of the spinal cord
Unipolar neurons in a ganglion

Multipolar neuron

High magnification of a multipolar neuron

Pseudo-unipolar neuron

High magnification of a pseudo-unipolar neuron
High magnification of a pseudo-unipolar neuron

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© januarie 2008 marius loots