Identify microscopically:

1. The fibrous capsule of the liver (capsule of Glisson)

2. Liver lobules

3. Liver parenchyme

4. Vena centralis

5. Portal areas

Draw and annotate:

A cross-section of a liver lobule of the pig.

1. What is the shape of the liver lobules?
2. What types of cells are found in the lobules?
3. How is the liver parenchyme arranged?
4. What comprise the portal areas, and where are they found?
5. How are the structures of each portal area distinguished from each other?

Variable magnification

• Slide demonstrating the general structure of the liver
• Classic liver lobule

• Classic liver lobule
• Central vein morphology
• Hepatocytes

• Compare H&E and silver stain for distribution of reticular fibres

Very low magnification

Classical and portal lobule and liver acinus
Functional areas of the liver acinus

Low magnification

Medium magnification

High magnification

Clinical case